Preprints

Brunner syndrome associated MAOA dysfunction in human dopaminergic neurons results in NMDAR hyperfunction and increased network activity.

Gamete simulation improves polygenic transmission disequilibrium analysis.

Distinct ensembles in the noradrenergic locus coeruleus evoke diverse cortical states.

Demyelination induces selective vulnerability of inhibitory networks in multiple sclerosis.

Heterozygous deletion of SYNGAP enzymatic domains in rats causes selective learning, social and seizure phenotypes.

A causal study of bumetanide on a marker of excitatory-inhibitory balance in the human brain.

Regulation of neural gene expression by estrogen receptor alpha.

TRAP-based allelic translation efficiency imbalance analysis to identify genetic regulation of ribosome occupancy in specific cell types in vivo.

Insights into dispersed duplications and complex structural mutations from whole genome sequencing 706 families.

Systematic evaluation of genome sequencing as a first-tier diagnostic test for prenatal and pediatric disorders.