Funded Projects
SFARI Funded Publications
De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor
Xu Y., Song R., Perszyk R.E., Chen W., Kim S., Park K.L., Allen J.P., Nocilla K.A., Zhang J., XiangWei W., Tankovic A., McDaniels E.D., Sheikh R., Mizu R.K., Karamchandani M.M., Hu C., Kusumoto H., Pecha J., Cappuccio G., Gaitanis J., Sullivan J., Shashi V., Petrovski S., Jauss R.T., Lee H.K., Bozarth X., Lynch D.R., Helbig I., Pierson T.M., Boerkoel C.F., Myers S.J., Lemke J.R., Benke T.A., Yuan H., Stephen F. Traynelis
Clinical features, functional consequences, and rescue pharmacology of missense GRID1 and GRID2 human variants.
Allen J.P., Garber K.B., Perszyk R., Khayat C.T., Kell S.A., Kaneko M., Quindipan C., Saitta S., Ladda R.L., Hewson S., Inbar-Feigenberg M., Prasad C., Prasad A.N., Olewiler L., Mu W., Rosenthal L.S., Scala M., Striano P., Zara F., McCullock T.W., Jauss R.-T., Lemke J.R., MacLean D.M., Zhu C., Yuan H., Myers S.J., Stephen F. Traynelis
Classification of missense variants in the N-methyl-d-aspartate receptor GRIN gene family as gain- or loss-of-function.
Myers S.J., Yuan H., Perszyk R.E., Zhang J., Khan S., Nocilla K.A., Allen J.P., Bain J.M., Lemke J.R., Lal D., Benke T.A., Stephen F. Traynelis