Mohan Babu is Professor, Chancellors Research Chair in Network Biology and the Director of the Mitochondrial Systems (mitoSYSTEMS) Research Centre for Chronic Disease at the University of Regina.
Babu is a leader in protein mass spectrometry (MS) and helped pioneer high-throughput MS- related techniques for the design and execution of groundbreaking genome-scale mapping of protein or genetic interaction networks in yeast, bacteria and mammalian brain tissue (including both neuronal and non-neuronal cells). His lab addresses research problems in basic and clinical science as well as complex systems biology through innovative technologies using proteomics and quantitative genetics. He has pioneered the mapping of native membrane protein complexes by affinity purification or co-fractionation followed by MS profiling in prokaryotes and eukaryotes.
Babu’s work defined the global landscape of the soluble and membrane interactome and has identified perturbed protein interactions in ASD. His lab also has a proven track record in the integrative bioinformatic analysis of complex ‘omic’ datasets and in the functional characterization of interacting proteins. His studies have revealed mechanisms underlying potential new physical connections between protein pairs, complexes and pathway relationships relevant to human health and diseases.
Babu is the recipient of numerous awards, including a Maud Menten New Principal Investigator Finalist Prize from the Canadian Institutes of Health Research and a Mid-Career Impact Award from the Saskatchewan Health Research Foundation. He has also been a treasurer for the Canadian Society of Microbiologists, an editorial board member of various scientific journals and a member of the board of directors for the Canadian Society for Molecular Sciences and Canadian National Proteomics Network.