This issue of the SFARI newsletter includes: (1) Updates to SFARI’s 2021 requests for grant applications, (2) SFARI 2020 Director Awards announced, (3) A message from SFARI regarding anti-Asian violence, (4) Simons Searchlight: April 2021 data release, (5) SFARI meeting report: SFARI Fall 2020 science meeting highlights new developments in autism research, (6) A Conversation with SFARI Bridge to Independence Investigator Aakanksha Singhvi, (7) Highlights of SFARI-funded research, (8) 2021 Human Cognitive and Behavioral Science — Request for applications, (9) 2021 Pilot Award — Request for applications, (10) SFARI Supplement to Enhance Equity and Diversity (SEED) — Request for applications, (11) Upcoming lecture: Jake Gratten and Naomi Wray, “New research results from the Australian Autism Biobank Study, (12) Upcoming lecture: Federico Bolognani, Stuart Cobb, Yael Weiss, and Randal Carpenter, “Small molecules, genes and antisense oligonucleotides: Industry perspectives on treatment development for ASD, (13) Upcoming lecture: David Ledbetter, Joseph Buxbaum, and Heather Mefford, “What do we mean by ‘autism risk genes’?”, (14) Past lecture: Elizabeth Berry-Kravis, “Clinical trials and cyclic AMP in fragile X syndrome: A life journey”.