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One brain, many genomes: Somatic mutation and genomic variability in human cerebral cortex

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 27 April 2016, Christopher Walsh reviewed recent work on ‘somatic mutations’ — de novo mutations that are present in some brain cells but not in all cells of the body — in several neurological conditions associated with intellectual disability and seizures. His talk was part of the Simons Foundation Autism Research lecture series....

Sleep in autism spectrum disorders: A window to etiology, diagnosis and treatment

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 7 September 2016, Ruth O'Hara discussed the field’s current understanding of sleep in autism spectrum disorder. Her talk was part of the Simons Foundation Autism: Emerging Concepts lecture series. About the Lecture Understanding sleep physiology in autism spectrum disorder (ASD) not only provides a window to the underlying etiology, it can also help...

Tuberous Sclerosis: Shedding light on the neural circuitry of autism

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 5 October 2016, Mustafa Sahin presented an update on translational research in Tuberous Sclerosis Complex. His talk was part of the Simons Foundation Autism Research lecture series. About the Lecture In this lecture, Mustafa Sahin presented the rationale for investigating Tuberous Sclerosis Complex (TSC) as a way to understand the cellular and circuitry...

How immune cells help wire the brain: Implications for autism and psychiatric illness

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 2 November 2016, Beth Stevens discussed recent work that implicates brain immune cells, called microglia, in sculpting of synaptic connections during development and their relevance to autism, schizophrenia and other brain disorders. Her talk was part of the Simons Foundation Autism Research lecture series. About the Lecture Recent research has revealed a key...

SFARI Society for Neuroscience 2016 Social

Hilton San Diego Bayfront Indigo 204 One Park Blvd, San Diego, CA, United States

  All Society for Neuroscience (SfN) attendees are welcome to join SFARI Investigators and scientific staff for an evening of socializing and networking, including a brief information session on SFARI funding opportunities and scientific resources for the autism research community. We welcome newcomers to autism research as well as those already working to uncover the...

Potholes and progress on the road to translational treatments in autism spectrum disorder

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 25 January 2017, Jeremy Veenstra-VanderWeele outlined critical challenges to translating genomic, cellular, and animal model research into new treatments for autism spectrum disorder. His talk was part of the Simons Foundation Autism Research lecture series. About the Lecture Emerging genomic and neuroscience findings have delivered hypotheses that are now being tested in autism...

Exploiting genetics to identify environmental risks for autism

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 22 February 2017, Mark Zylka described how candidate environmental risk factors for autism can be identified rationally, by pinpointing chemicals that interfere with the same molecular pathways that are affected in individuals with autism. His talk was part of the Simons Foundation Autism Research lecture series. About the Lecture Our inability to identify...

What can genetics tell us about autism spectrum disorder?

Gerald D. Fischbach Auditorium 160 5th Avenue, New York, NY, United States

  On 22 March 2017, Stephan Sanders presented an update on the current state of genetics research in autism, highlighting some of the key findings that remain to be discovered, and discussing how these findings could ultimately benefit individuals with autism and their families. His talk was part of the Simons Foundation Autism Research lecture...

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