SPARK (Simons Foundation Powering Autism Research for Knowledge) is an autism research initiative that aims to recruit, engage and retain a community of 50,000 individuals with autism and their family members living in the U.S.

Participation in this cohort involves the contribution of medical and behavioral information, mailing in saliva for genetic analysis, the potential option to have genetic findings related to autism returned, and the option to be recontacted to participate in future research studies. This community of engaged participants will provide researchers with an efficient way to invite individuals to participate in their research.

This research project is centrally coordinated by the Simons Foundation Autism Research Initiative (SFARI) and includes collaboration with 25 university-affiliated research clinics in 22 states across the U.S. SFARI launched a pilot phase of the project in December 2015 with three clinical sites. An additional 18 sites began recruiting individuals with autism and their families in April 2016 and the remaining sites began recruitment in April 2017.

In addition, numerous national and local autism community organizations across the U.S. are partnering with SFARI to help recruit participants and spread the word about this landmark study.

Researchers can request de-identified phenotypic data and submit an application to recruit SPARK participants into new autism research studies through SFARI Base. The SPARK Recruitment Process Document provides answers to many frequently asked questions.

Families who are interested in learning more about SPARK or in participating can visit

SPARK data

Phenotypic data from 46,603 individuals are currently available to approved researchers via SFARI Base. These individuals include:

  • 6,309 trios (individuals with ASD and both biological parents)
  • 15,302 children (under 18 years of age) with ASD
  • 2,787 adults with ASD
  • 12,717 males with ASD
  • 3,254 females with ASD
  • 7,610 unaffected siblings
  • 682 enrolled twins, triplets and quadruplets
  • 1,944 multiplex families

Genomic data are available for 469 trios.

Clinical sites

Community partners

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