Bridge to Independence Award Program
SFARI is invested in supporting the next generation of top autism researchers. The Bridge to Independence Award program engages talented early-career scientists to pursue autism research by facilitating their transition to research independence and providing grant funding at the start of their faculty positions at a U.S. or international research institution.
Applications from groups that have been historically underrepresented or excluded in the biomedical workforce, including but not limited to racial and ethnic groups, sexual orientation and gender identities, individuals with mental/physical disabilities and those from economically disadvantaged backgrounds, are encouraged.
Request for applications (RFA) open each year and are aimed at scientists with a Ph.D. and/or M.D. who are currently in training positions but intend to seek tenure-track research faculty positions during the upcoming academic job cycle. Fellows will receive up to two (2) years of postdoctoral fellowship support with an annual salary of $70,000, fringe benefits, an annual resource and professional development allowance of $10,000, and indirect costs (limited to 20 percent of modified total direct costs, see Simons Foundation policies) followed by a commitment of $600,000 over three (3) years, including indirect costs (limited to 20 percent of modified total direct costs, see Simons Foundation policies) activated upon assumption of a tenure-track research professorship.
- SAM opens for applications
- RFA informational Zoom session
- First-stage applications and letters of recommendation due
- Finalists invited for interviews
- Virtual interviews
June 1 and 2, 2023 - BTI fellows notified of award
June 2023
- SAM opens for applications
- RFA informational Zoom session
- First-stage applications and letters of recommendation due
- Finalists invited for interviews
- Virtual interviews
June 1 and 2, 2023 - BTI fellows notified of award
June 2023
- Scientific inquiries:
[email protected] - Administrative inquiries:
[email protected] - Simons collections inquiries:
[email protected] - Technical Assistance:
[email protected] - Monday - Friday: 9 am - 5 pm ET
SF offices are closed December 23 - January 2
- SAM opens for applications
- RFA informational Zoom session
- First-stage applications and letters of recommendation due
- Finalists invited for interviews
- Virtual interviews
June 1 and 2, 2023 - BTI fellows notified of award
June 2023
- Scientific inquiries:
[email protected] - Administrative inquiries:
[email protected] - Simons collections inquiries:
[email protected] - Technical Assistance:
[email protected] - Monday - Friday: 9 am - 5 pm ET
SF offices are closed December 23 - January 2
Application Process
Bridge to Independence (BTI) grants are awarded through a multi-stage process. The first stage is a competitive process in which first-stage applications are reviewed by the SFARI science team and an external scientific panel. BTI fellows are selected at the end of stage one. Upon selection as a BTI fellow, fellows will receive up to two (2) years of postdoctoral support at their postdoc institution with an annual salary of $70,000, as well as a resource and professional development allowance of $10,000 per year. The award will provide fringe benefits and indirect costs (limited to 20 percent of modified total direct costs, see Simons Foundation policies). During this time, postdocs will receive mentorship and professional development resources to assist in their search for a faculty position.
Fellows have 24 months to secure a tenure-track professorship at an academic institution and submit a second-stage approval application. Review of the approval application is a non-competitive, internal process intended to confirm that the fellow has secured an academic research position and adequate institutional resources to accomplish the BTI research proposal. After the Simons Foundation accepts the approval application, fellows may activate their BTI grants, which provide $600,000 over three (3) years, including indirect costs (limited to 20 percent of modified total direct costs, see Simons Foundation policies), awarded through their faculty appointment institution. The award is administered through the institution at which the BTI fellow has secured a tenure-track faculty appointment. Funds are intended as a supplement to a standard start-up package.
Awards will be governed by the Simons Foundation policies, which can be found at http://www.simonsfoundation.org/funding/Simons Foundation policies/.
Eligibility
New for 2023: The award program has removed the requirement that the tenure-track position be at a U.S. or Canadian institution. Additionally, please note that beginning with the 2024 SFARI BTI RFA, applicants will be limited to one application resubmission (a total of two submissions to the BTI RFA).
- Applicants must hold a Ph.D., M.D. or equivalent degree.
- Applicants must be currently in non-independent, mentored training positions, as recognized by their institution. The following guidelines should be used to distinguish independent from non-independent positions (modified from the National Institutes of Health (NIH) K99/R00 program announcement eligibility section):
Evidence for non-independence may include:- The applicant has a postdoctoral fellowship.
- The applicant’s research is entirely funded by another investigator’s grants.
- The applicant’s research is conducted entirely in another investigator’s assigned space.
- According to institutional policy, the applicant is not allowed to submit an application for an NIH R01 research project grant.
Conversely, evidence for independence, and therefore lack of eligibility, includes:
- The applicant has a full-time faculty position. Exception: A clinician who holds a faculty member position in order to fulfill their clinical responsibilities but who does not hold an independent research faculty position may still be eligible. Such individuals should contact the foundation to confirm their eligibility prior to submitting their applications.
- The applicant received a start-up package for support of the applicant’s independent research.
- The applicant has research space dedicated to the applicant’s own research.
- The applicant is eligible to apply for independent research funding as the PI of an NIH R01 research project grant.
- Applicants must be actively seeking a tenure-track position at an institution of higher education during the 2023-2024 academic year.
- Applicants are not eligible if they are recipients of other career development awards with similar budgetary scopes as the SFARI BTI Award. These include, but are not limited to:
- NIH K99/R00 (please note that other K awardees may be eligible, e.g., recipients of K01 and K08)
- Burroughs-Wellcome Fund Career Award
- American Academy of Neurology Career Development Award
- Howard Hughes Medical Institute Hanna H. Gray Fellowship
You are strongly encouraged to contact SFARI before applying if you believe your career development award is comparable to the BTI Award, but it is not listed above.
- Applicants must not have accepted a formal offer for a tenure-track faculty position prior to 2023 RFA decision notifications, which for the 2023 application cycle will be sent in June 2023.
- There are no citizenship requirements.
All potential applicants with questions about eligibility are strongly encouraged to contact SFARI at [email protected] before submitting an application.
All applicants with a change in their eligibility status, due to acceptance of a faculty position or grant of similar budgetary scope to the SFARI BTI Award, should notify SFARI without delay at [email protected].
Level and Duration of Funding
BTI Postdoctoral Award
BTI fellows will receive up to two (2) years of postdoctoral support at their postdoc institution with an annual salary of $70,000. During this time, fellows will also receive mentorship and professional development resources, as well as a resource and professional development allowance of $10,000 per year, to assist in their search for a faculty position. The award will provide fringe benefits and indirect costs (limited to 20 percent of modified total direct costs, see Simons Foundation policies).The resource and professional development allowance will be awarded through the current (postdoctoral) institution for the fellow’s exclusive and flexible use for a variety of purposes, including but not limited to laptop and software purchases, conference-related expenses, workshops and other professional development costs.
BTI Faculty Award
After the Simons Foundation accepts the second-stage approval application, the awardee will receive research support of $600,000 over three (3) years, including indirect costs (limited to 20 percent of modified total direct costs, see Simons Foundation policies).The award is administered through the institution at which the BTI fellow has secured a tenure-track faculty appointment. Funds may not be used toward the faculty salary but may provide salary support for other laboratory personnel and other typical grant budget expenditures. Institutional start-up packages may not be reduced because of BTI funding. SFARI will work with fellows and their potential faculty institutions to ensure that fellows receive start-up packages with sufficient institutional resources and academic privileges to complete the BTI project.
Informational Session for Potential Applicants
An RFA informational Zoom meeting, featuring SFARI science staff and current SFARI BTI fellows, was held on December 8, 2022 at 12:00 p.m. EST. We encourage prospective applicants to view the recording here.
The Simons Foundation held an informational session on how to submit an application through our new grants management system, Simons Award Manager (SAM), on Thursday, January 12 – Click here to watch the recording.
Additionally, informational videos on submitting applications in SAM can be found here.
Instructions for submission
The deadline for receipt of the first-stage application is 12:00pm EST on February 16, 2023. Applications must be submitted via SAM). Please click on the Funding Opportunities icon and navigate to the Simons Foundation Autism Research Initiative — Bridge to Independence Award call. Click the Create Application button to begin. Applications should be started and submitted under the applicant’s own account in SAM.
Please note that anyone submitting an application will be added to the SFARI newsletter mailing list.
First-stage applications should include the following (for more details, see the “Instructions” document, available for download in SAM):
- Specific Aims Page. The Specific Aims Page should not exceed one (1) page and should be a summary of the proposed project you intend to accomplish in the first three (3) years of your independent professorship. This should focus on the research aims of the project, including a concise rationale for the hypothesis, description of feasibility/preliminary data and experimental approach, and impact on autism research.
- The proposal narrative. This should be no more than three (3) pages long (NOT including references, tables and figures) describing the project you intend to accomplish in the first three (3) years of your independent professorship. The proposal narrative should be considered an expanded version of the Specific Aims Page and used to provide more detail on the following:
- Relevant scientific background
- Feasibility/preliminary results when applicable
- Specific aims
- Experimental design
- Pitfalls and alternative strategies
- Project significance and relevance to autism
- Timeline and milestones
- Overview of scientific interests and goals describing your overall future research program as an independent investigator and how autism science fits in with your intended research program. This should be no more than one (1) page.
- Please upload a biosketch for the PI using the provided template or NIH- or NSF-style format.
- Letter from current institution officially confirming you are in a mentored training position (e.g., letter from department chair or grant office).
- Letters of recommendation (separate, blind submission; deadline 16 February 2023). Three (3) letters of recommendation are required from current or former mentors, or other senior scientists who have substantial familiarity with your scientific career thus far. At least one letter of recommendation must be from a current scientific mentor. Confidential letters must be submitted through SAM.
- Budget: A detailed budget for up to two (2) years of postdoctoral support, specifically: $70,000 annual salary and fringe, for the fellow (personnel field), $10,000 annual resource and professional development allowance (research support costs field), and indirect costs (limited to 20 percent of modified total direct costs, see Simons Foundation policies).
First-stage applications are reviewed by the SFARI science team and competitive applications are further reviewed by an external scientific panel. Reviewers will weigh criteria related to the applicant’s scientific potential as an independent investigator and their ability to formulate an impactful, innovative and feasible autism research project.
After Selection
2023 BTI fellows will be notified of their status by June 2023. Fellows will receive up to two (2) years of postdoctoral support with a $70,000 annual salary, awarded to them at their postdoc institution. In order to receive the postdoctoral support portion of the award, your institution must appoint you as an employee of the university with no teaching obligation and provide the standard benefits package that the university provides to employees. Upon notification, BTI fellows have up to 24 months to secure a tenure-track faculty position and submit an approval application. As job negotiations develop, fellows are strongly encouraged to contact their SFARI science manager. SFARI will informally review job offer letters and, as appropriate, work with fellows and their potential faculty institutions to ensure that start-up packages provide sufficient institutional resources and academic privileges to complete the BTI project.
To activate the faculty support portion of the award, fellows must submit a second-stage approval application, which includes the tenure-track faculty appointment offer letter with confirmed research startup package and laboratory space commitments. Other required documents include applicable updates to the proposal narrative, biosketch, current and pending support, budget, budget justification, research environment and resources, renewable reagents and data-sharing plan, and signature page.
SFARI will review these documents internally with the intention of funding all fellows who have secured sufficient institutional resources and academic privileges to complete the BTI project. If these are deemed acceptable, a grant funding letter will be sent.
SFARI reserves the right to withhold grant support 1) if the fellow is unable to secure a tenure-track position at a suitable academic institution within 24 months of their award notification letter, 2) if an institutional environment is deemed inadequate by SFARI to support successful completion of the research project, 3) if the revised and updated research plan is not considered adequate, or 4) if the fellow is unable to fulfill the responsibilities of the PI for other reasons. Such instances will be handled on a case-by-case basis. It is our intention that withholding grant support from fellows will occur only in rare instances. When appropriate, SFARI will work with fellows and their prospective institutions in developing mutually agreeable solutions.
Our Commitment to Diversity, Equity and Inclusion
Applications from groups that have been historically underrepresented or excluded in the biomedical workforce, including but not limited to racial and ethnic groups, sexual orientation and gender identities, individuals with mental/physical disabilities and those from economically disadvantaged backgrounds, are encouraged.
Many of the greatest ideas and discoveries come from a diverse mix of minds, backgrounds and experiences. The Simons Foundation is committed to grantmaking that inspires and supports greater diversity and inclusiveness by cultivating a funding environment that ensures representation of all identities and differences and equitable access to information and resources for all applicants and grantees.
The Simons Foundation provides equal opportunities to all applicants for funding without regard to race, religion, color, age, sex, pregnancy, national origin, sexual orientation, gender identity, genetic disposition neurodiversity, disability, veteran status or any other protected category under federal, state and local law. The foundation also funds programs directed at supporting scientists from disadvantaged backgrounds or underrepresented groups, often working closely with professional societies and other funding agencies.
- SAM opens for applications
- RFA informational Zoom session
- First-stage applications and letters of recommendation due
- Finalists invited for interviews
- Virtual interviews
June 1 and 2, 2023 - BTI fellows notified of award
June 2023
- Scientific inquiries:
[email protected] - Administrative inquiries:
[email protected] - Simons collections inquiries:
[email protected] - Technical Assistance:
[email protected] - Monday - Friday: 9 am - 5 pm ET
SF offices are closed December 23 - January 2
The deadline for first-stage application submission is 16 February 2023 at 12:00 p.m. EST.
Applications must be submitted via the Simons Award Manager (SAM). Please click on the Funding Opportunities icon and navigate to the Simons Foundation Autism Research Initiative – Bridge to Independence Postdoctoral Award call. Click the Create Application button to begin. Applications should be started and submitted under the applicant’s own account in SAM.
Informational Session for Potential Applicants
The Simons Foundation held an informational session on how to submit an application through our new grants management system, Simons Award Manager (SAM), on Thursday, January 12 – Click here to watch the recording.
Additionally, informational videos on submitting applications in SAM can be found here.
First-Stage Application Requirements and Submission Instructions
To submit a first-stage application, the following sections must be completed in SAM:
- Proposal Tab:
- Applicant Details & Personal Data: Enter required fields. The applicant may edit information via the Edit Profile button as needed.
- Academic Degrees: Click the Add/Modify Degree(s) button to provide this information.
- Application Details: Provide the required information. Hovering over the question mark icons will provide additional information on required fields.
- Proposal – The following information/upload must be provided:
- Mentor name.
- Specific Aims: Upload via template provided.
- Proposal Narrative: Upload via template provided.
- Scientific Interests and Goals: Upload via template provided.
- Confirmation Letter for Mentored Training Position: Provide a letter from your current institution officially confirming that you are in a mentored training position (e.g., letter from department chair or grant office).
- Personnel Biosketches: Applicant should upload their biosketch using template provided and/or NIH or NSF-style format.
- Contacts & Personnel Tab:
- Institution Administrative Contacts: You must add at least one institution signing official and financial officer to the Institution Administrative Contacts section before you will be able to submit your application.
- Project Personnel: Please indicate all key personnel on the proposed project. Project personnel who will be named in the budget must be added to the Project personnel section on this tab before they will display as available options in the budget module. This does not apply to TBD personnel.
- Budget Tab:
- Click the Edit/Modify button to add a detailed budget for up to two (2) years of postdoctoral support, specifically: $70,000 annual salary, and fringe, for the fellow (personnel field), $10,000 annual resource and professional development allowance (research support costs field), and indirect costs (limited to 20 percent of modified total direct costs, see Simons Foundation policies).
- Letter of Reference Tab:
- Three (3) confidential letters of recommendation are required from current or previous mentors and/or senior scientists who have substantial familiarity with your scientific career thus far. At least one letter of recommendation must be from a current scientific mentor. Confidential letters must be submitted through SAM.
- Instructions on how to invite referees are provided in this tab within SAM. Please note that you must enter a date by which the invited referee should submit their letter of reference and click Save Draft prior to sending the invitation. This will ensure that the email invitation sent to the referee includes the due date you set. A video on the letter of reference process can be found here.
- You will not be able to submit your application until all three letters of reference are submitted by the referees.
- Publications & Other Support Tab:
- Publications: Follow instructions for providing publications for all key personnel on the project. Publications can be added as a batch from a Pubmed search by selecting Select publication from profile and then clicking the Assign Publications for this Proposal button. Note that publications will be used to determine conflicts of interest (COIs) for the review of your proposal; including a complete list of your publications over the last seven years using this function, rather than the PDF upload option, will expedite the review process.
- Other Support: Follow instructions for providing other support information for all key personnel on the project.
- If using PDF upload, use NIH format.
- Check Application Progress: Click the Check Application Progress button to check for any missing required information or files. All missing required information will be listed at the top of the screen and must be corrected before the application can be submitted.
- Send for Sign-off: When the application is complete, click on the Send for Sign-off button to send to your signing official for signature. You will receive a notification when the application is signed.
- Submit Application: When the full proposal application is complete and signed, please click on the Submit Application button. A confirmation page will appear once the application is successfully submitted. It will appear in the Submitted tab of the Applications in Progress table. Please note that you will not be able to submit an application if the deadline has passed.
Please note that research proposals exceeding the three (3)-page limit will not be reviewed. No extensions will be given.
- SAM opens for applications
- RFA informational Zoom session
- First-stage applications and letters of recommendation due
- Finalists invited for interviews
- Virtual interviews
June 1 and 2, 2023 - BTI fellows notified of award
June 2023
- Scientific inquiries:
[email protected] - Administrative inquiries:
[email protected] - Simons collections inquiries:
[email protected] - Technical Assistance:
[email protected] - Monday - Friday: 9 am - 5 pm ET
SF offices are closed December 23 - January 2
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Eligibility
- The applicant’s research is entirely funded by another investigator’s grants.
- The applicant’s research is conducted entirely in another investigator’s assigned space.
- According to institutional policy, the applicant is not allowed to submit an application for an NIH R01 research grant as the principal investigator (PI).
- The applicant has a full-time faculty position.
- The applicant received a startup package for support of the applicant’s independent research.
- The applicant has research space dedicated to the applicant’s own research.
- The applicant is eligible to apply for an NIH R01 as the PI.
- NIH K99/R00 (please note that other K awardees may be eligible, e.g., recipients of K01 and K08)
- Burroughs Wellcome Fund Career Award
- American Academy of Neurology Career Development Award
- Howard Hughes Medical Institute Hanna H. Gray Fellowship
I do not have a Ph.D. or M.D. yet, but I am currently pursuing one (e.g., I am a current graduate or medical student). Am I eligible?No. Applicants must hold a Ph.D., M.D. or equivalent degree. Please note that the foundation does not consider a Doctor of Psychology degree, e.g., Psy.D., as equivalent to a Doctor of Philosophy degree, Ph.D.
Is there a limit to the number of postdoctoral training years for applicants?No. In recognition that different life trajectories can still culminate in successful scientific careers, SFARI has removed our previous six-year eligibility limit on postdoctoral training.
I already have a postdoctoral fellowship, am I eligible to apply?Yes. Please contact us to discuss options for the postdoc fellowship support portion of this award.
I have accepted a tenure-track faculty position but have not yet started. Am I still eligible?No. However, with approval of your faculty institution, you are eligible to apply for SFARI Pilot Awards, as well as targeted RFA programs. More information about these grant opportunities is available here.
I hold a non-tenured faculty position (e.g., assistant or adjunct professor) at my institution. Am I eligible to apply?No. However, exceptions are made for clinical faculty members who do not hold an independent research faculty position (see question 8).
I have a Ph.D. (or equivalent research doctorate degree) but do not have the title of ‘postdoctoral fellow.’ Am I eligible to apply?You are eligible only if your institutional title is the equivalent of ‘postdoctoral fellow’ — in other words, if you are considered to be in a non-independent training position with a designated mentor. Confirmation of your training status (e.g., letter from the department chair) is required for the first-stage application.
What is the difference between a non-independent and an independent position?As modified from the National Institutes of Health (NIH) K99/R00 program announcement, evidence for non-independence may include documentation that:
Conversely, independence, and therefore lack of eligibility, is indicated by any of the following:
I am a clinician (M.D., D.D.S., D.V.M. or other licensed professional) but do not have a postdoctoral fellow position. Am I eligible to apply?Clinicians who hold faculty positions in order to fulfill their clinical responsibilities may be eligible if and only if they do not hold independent research faculty positions. The foundation may require written confirmation of the distinction between the applicant’s clinical and research responsibilities. Please contact [email protected] to confirm eligibility status prior to application submission.
I am not a U.S. citizen. Am I eligible to apply?Yes. U.S. citizenship is not required.
Are there any eligibility restrictions on duration of postdoctoral training or how long ago I earned my Ph.D. or M.D.?No. SFARI does not restrict eligibility based on duration of postdoctoral training or how long ago the Ph.D., M.D. or equivalent degree was earned.
Is postdoctoral training a requirement to apply for the BTI Award?No. However, a postdoctoral fellowship is often considered essential training in preparation for an independent research career and, as such, the vast majority of competitive applicants have had substantive postdoctoral training. Nevertheless, SFARI acknowledges that some scientific fields (e.g., computer science) and some individuals may already be well placed to begin their professorships without having completed a postdoctoral fellowship. Our review criteria are focused on whether an applicant is currently poised to begin their independent careers, as evidenced by their scientific contributions and vision, and not based on whether the applicant has conducted postdoctoral training, per se.
I am the recipient of a career development award with a similar budgetary scope to the SFARI BTI Award. Am I eligible?No. These awards include, but are not limited to:
You are strongly encouraged to contact SFARI before applying if you believe your career development award is comparable to the BTI Award but is not listed above.
I applied for the SFARI BTI Award in a previous year and was not selected. Am I still eligible to apply?Yes. However, beginning with the 2024 SFARI BTI RFA, applicants will be limited to one application resubmission (a total of two submissions to the BTI RFA).
I noticed the Simons Collaboration on the Global Brain (SCGB) and the Simons Collaboration on Plasticity and the Aging Brain (SCPAB) are also offering independence awards. How are the three programs similar and different to each other, and may I apply to both?Simons Foundation Independence Award programs are currently offered through three divisions of the foundation. They share the common goal of supporting early career scientists as they transition from mentored training to their independent research positions. However, the three award programs emphasize different scientific missions and have different eligibility criteria. Please see the comparison chart on the website for more information about each.
Candidates may apply to more than one program in a single RFA cycle; however, each application will be reviewed individually based on the program’s own selection process and criteria. As such, it is expected that applicants will tailor each research narrative to align with the respective Simons Foundation program to which they are applying. Please note that selected candidates may only accept one Independence award.
If you have questions regarding about the suitability of your research narrative for the SFARI BTI program, please contact us at [email protected].
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First-Stage Application Submission
Can I email or mail an application?
No. The Simons Foundation only accepts applications submitted online through SAM.
Do I need to provide official documentation of my position as a mentored trainee?Yes. A letter from your institution (e.g., letter from department chair or grants office) officially confirming your status in a training position and specifying your designated mentor is a required document for the application.
Does the Simons Foundation require letters of recommendation?Yes. The foundation requires three (3) letters of recommendation from current or former mentors, or from other senior scientists who have substantial familiarity with your scientific career thus far. At least one (1) letter of recommendation must be from a current scientific mentor.
Confidential letters must be submitted through SAM. The applicant CANNOT submit the letters of recommendation directly. In the only application, applicants should enter in the names and email addresses of three (3) individuals who will upload recommendations on the applicant’s behalf directly into SAM.
Letters of recommendation must be submitted with the application by February 16, 2023, 12:00 p.m. EST. It is advised that applicants begin the online application at least four (4) weeks prior to the February 16 deadline to ensure that letters of recommendation are submitted in time. Applicants will not be able to submit their applications without the required references.
Do I need approval from the grants office at my institution to submit my first-stage application?Yes. Institutional sign-off is required in the first stage in order to receive the postdoctoral awards. An additional institutional signoff from your faculty institution will also be required at the second stage approval application if you are selected for an award.
Are references, figures and figure legends included in the narrative three (3)-page limit? How should they be included?No, references, figures and figure legends are not included in the page limit for the research proposal. Please attach them at the end of the narrative in the same PDF file. The Simons Foundation’s preference is for figures to follow the narrative rather than be embedded in the text.
What can I include in the Other section?“In-press” papers can be included as well as any papers that you consider essential for the work of the review committee, not more than three (3). Any other material should be included, if possible, in the narrative.
If you have video attachments for your proposal, please upload them as “Other” (all file types are accepted). All other documents should be uploaded in the “Proposal Attachments” section of the application.
May SFARI funds go toward providing clinical services or conducting a clinical trial?No. Proposals for clinical “efficacy” trials are not allowed. Funds may only be used toward a research project.
I get an error message citing a missing section when I try to submit.The Check Application Progress button reviews your proposal for missing sections. The submission instructions list the required sections and attachments. You must complete the missing items listed in the error message. If you are still receiving error messages after completing and saving the indicated sections, please contact [email protected].
How do I submit?When the full proposal application is complete, please click on the Submit Application button. A confirmation page will appear once the application is successfully submitted. It will appear in the Submitted tab of the Applications in Progress table. Please note that you will not be able to submit an application if the deadline has passed.
Can I make changes to the application once it has been submitted?You must contact the Simons Foundation prior to the February 16, 2023 deadline to un-submit your application. Please email [email protected] if you would like to un-submit your proposal for any modifications.
Will I receive a confirmation email when I submit?A confirmation email is sent upon submission. Make sure that spam filters allow emails from [email protected]. Additionally, the proposal will be in the Submitted tab of the Applications in Progress table after submission.
When will applicants be notified of their BTI fellow status?Applicants will be notified of their status in June 2023.
How are BTI fellows selected?All first-stage applications receive scientific review by our internal science team. Competitive proposals will receive additional review by an external scientific committee. The applicant’s potential promise as an independent investigator and commitment to autism research will be the strongest factors. However, the proposal must also outline an impactful, innovative and feasible autism study. Fellows will be chosen based on these criteria and the recommendations of our external scientific committee.
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Postdoctoral Award Funding
How does the Postdoctoral Award work?
As a SFARI BTI fellow, postdocs will be employees of their institutions and will receive an annual salary at their postdoctoral institution of $70,000 for up to two (2) years. The award will provide fringe benefits and indirect costs (limited to 20 percent of modified total direct costs, see Simons Foundation policies).Fringe will be added to this award; the fringe rate varies based on the institutional fringe rate and will not be adjusted mid-award. In addition to the annual salary, postdocs will receive a resource and professional development allowance of $10,000 per year for up to two (2) years. The resource and professional development allowance will be awarded through the current (postdoctoral) institution for fellow’s exclusive and flexible use for a variety of purposes, including, but not limited to laptop and software purchases, conference-related expenses, workshops and other professional development costs.
Will I be eligible for health insurance and other benefits during the Postdoctoral Award stage?In order to receive the postdoctoral support portion of the award, your institution must appoint you as an employee of the university with no teaching obligation, and provide the standard benefits package (e.g., health insurance, retirement plan, etc.) that the university provides to employees.
What if I get a faculty position in under two years? What will happen to the postdoc support funds?If a postdoc starts their faculty position in less than two years, any unexpended balance must be returned to the Simons Foundation.
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Second-Stage Application Submission and Faculty Award Funding
- Copy of tenure-track faculty appointment letter with confirmed research start-up package and laboratory space commitments
- Updated research proposal—given the time lag between the initial submission of the fellow’s first-stage application and activation of the grant, SFARI allows the fellow to update their research proposal as long as the project remains within scope of the original proposal.
- Updated biosketch for the PI
- Current and pending support for the PI
- Budget — BTI funds may not be used toward the PI’s salary or general lab equipment such as freezers and refrigerators.
- Budget justification
- Research environment and resources — investigators should demonstrate access to appropriate facilities and resources for successful completion of the proposed research grant.
- Data-sharing plan
- Institutional sign-off
What is the funding period? When will funding begin?Once the approval application has been submitted, SFARI will coordinate with the fellow about the timing of the award letter and start date. The newly-appointed principal investigator (PI) will receive research support at the level of $600,000 over three (3) years, including indirect costs (limited to 20 percent of modified total direct costs, see Simons Foundation policies).The award is administered through the institution at which the PI has a tenure-track faculty appointment.
What can funds be used for?It is expected that proposed budgets reflect the accurate proportion of resources (e.g., personnel, supplies, equipment, travel) needed to complete the SFARI-funded project. Funds may be used toward salary and tuition support for laboratory personnel but may not be used toward the PI’s salary. In addition, since it is expected that all awardees will receive institutional start-up packages, we strongly discourage budget allocations for general lab equipment, such as freezers and refrigerators. All budgets must be approved by SFARI before funding may begin. Institutional startup packages may not be reduced because of SFARI funding.
May I accept a position in the department where I conducted my mentored research?Fellows are encouraged (but not required) to apply for independent positions in different departments and institutions from where they conducted their mentored research. It is important for all fellows, but especially fellows who intend to stay at their mentoring institution for their independent role, to discuss their intentions with their SFARI science manager. Fellows who accept faculty positions at their mentoring institutions may be asked to submit a letter from their department chair outlining their commitment and plans for ensuring the fellow’s independence.
I am a BTI fellow and am close to receiving a tenure-track faculty offer letter. What do I do now?Contact your SFARI science manager, who will informally review your offer letter to flag any potential issues with activating the grant. As appropriate, SFARI will work with fellows and their potential faculty institutions to ensure that start-up packages provide sufficient institutional resources and academic privileges to complete the BTI project.
Once you are within 2-3 months of beginning work on your BTI project, you must submit your award approval application in order to formally activate your BTI grant. To do this, you must submit the following documents through your appointment institution, using SAM:
SFARI reserves the right to withhold grant support 1) if the fellow is unable to secure a tenure-track position at a suitable academic institution within two years of receiving their fellows designation letter, 2) if an institutional environment is deemed inadequate by SFARI to support successful completion of the research project, 3) if the revised and updated research plan is not considered adequate, or 4) if the fellow is unable to fulfill the responsibilities of the PI for other reasons. Such instances will be handled on a case-by-case basis. It is our intention that withholding grant support from fellows will occur only in rare instances.
2022
Cheen Euong Ang, Ph.D.
Cheen Euong Ang is currently a postdoctoral fellow in the lab of Xiaowei Zhuang at Harvard University where he focuses on developing transcriptome and epigenome imaging methods. He received his B.Sc. from McGill University and his Ph.D. from Stanford University. His Ph.D. thesis work in the lab of Marius Wernig centered on developing protocols for neuronal reprogramming and applying them to model neuropsychiatric diseases.

Anila D’Mello, Ph.D.
Anila D’Mello is a postdoctoral fellow at the McGovern Institute for Brain Research at the Massachusetts Institute of Technology working with John Gabrieli. She received her B.A. in psychology from Georgetown University, and completed her Ph.D. in behavior, cognition and neuroscience at American University. D’Mello’s doctoral and postdoctoral research has leveraged neuroimaging, neuromodulation and behavioral experimentation to understand cerebellar contributions to language, social communication and cognition in individuals with and without autism spectrum disorders.

Ryoma Hattori, Ph.D.
Ryoma Hattori is an assistant project scientist at the University of California, San Diego. He received his B.S. from the University of Tokyo and A.M. and Ph.D. from Harvard University. He completed his doctoral thesis work in the laboratory of Takao K. Hensch, where he studied the developmental dynamics of multisensory interactions in the mouse visual cortex and related changes in mouse models of autism.

Leanna M. Hernandez, Ph.D.
Leanna Hernandez is a postdoctoral fellow at the University of California, Los Angeles (UCLA). She earned her Ph.D. in neuroscience in the laboratory of Mirella Dapretto, where her dissertation work used magnetic resonance imaging to characterize the impact of genetic variability in the OXTR gene on neurobiological heterogeneity and sex-differences in autism spectrum disorder (ASD).

Katie Matho, Ph.D.
Katie Matho is a research investigator at Cold Spring Harbor Laboratory. She received her B.S. from Union College, and her M.S. and Ph.D., both in neuroscience, from Sorbonne Université in Paris, France. For her Ph.D. work with Jean Livet at Institut de la Vision in France, Matho mapped the microscale connectivity of auditory circuitry in the brainstem, in the emerging field of connectomics. She employed a multicolor “barcoding” strategy called “Brainbow,” whereby neurons express random combinations of fluorescent proteins, facilitating single-cell, large-volume image analysis. This technique enabled her to identify previously unknown instances of converging inputs within this circuit where 1:1 connectivity is thought to be the rule.

Martin Munz, Ph.D.
Martin Munz is a postdoctoral fellow in the lab of Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel. He is interested in understanding the role of activity during the inception of cortical circuits. Specifically, he developed imaging, molecular and electrophysiological techniques to allow the in vivo observation and manipulation of developing embryonic cortical circuits in mice. He plans to describe cell type-specific changes that occur in mice with autism-related mutations during embryonic development.

Michael Segel, Ph.D.
Michael Segel is a postdoctoral fellow at the Broad Institute of MIT and Harvard. He received his A.B. from Harvard College in human developmental and regenerative biology and his Ph.D. in clinical neuroscience from the University of Cambridge. For his doctoral thesis in the lab of Robin Franklin, he explored the molecular mechanisms underpinning the aging of glia in the central nervous syste

2021
Gabriella Boulting, Ph.D.
Gabriella Boulting earned a Ph.D. in biochemistry in the laboratory of Kevin Eggan in the Stem Cell and Regenerative Biology Department at Harvard University, where she focused on the application of human pluripotent stem cells (PSCs) to study neurogenerative disease. She developed methods to produce human spinal motor neurons in vitro, generated a vetted panel of human PSC lines for in vitro amyotrophic lateral sclerosis (ALS) disease modeling and uncovered disease phenotypes in motor neurons derived from induced PSCs from individuals with ALS.

Alexander Li Cohen, M.D., Ph.D.
Alexander Li Cohen is a physician-scientist and instructor in the Department of Neurology at Boston Children’s Hospital and Harvard Medical School. He received his B.A. in biology and biomedical physics from Washington University in St. Louis and his M.D. and Ph.D. degrees from Washington University School of Medicine in St. Louis. He then completed residency training in pediatrics and child neurology at Mayo Clinic in Rochester, Minnesota, and clinical and post-doctoral fellowships in pediatric behavioral neurology and translational research in neurodevelopmental disorders at Boston Children’s Hospital.

Eirene Markenscoff-Papadimitriou, Ph.D.
Eirene Markenscoff-Papadimitriou is a postdoctoral fellow at University of California, San Francisco (UCSF). She received her B.A. from Harvard College and her Ph.D. in Neuroscience at UCSF. For her doctoral thesis in the laboratory of Stavros Lomvardas, she explored the regulation of olfactory receptor genes and discovered a unique mode of gene regulation that involves inter-chromosomal interactions in the nucleus.

Marino Pagan, Ph.D.
Marino Pagan is a postdoctoral research associate at Princeton University. He received his B.S. in computer engineering and his M.S. in control engineering from Scuola Superiore Sant’Anna and University of Pisa in Italy. He completed his Ph.D. in neuroscience at University of Pennsylvania in the laboratory of Nicole Rust, where he studied the neural circuits of visual object search in macaque monkeys using electrophysiology and computational modeling.

Kartik Pattabiraman, M.D., Ph.D.
Kartik Pattabiraman is an Alfred J. Solnit Integrated Psychiatry Fellow at the Yale Child Study Center. He received his Sc.B. from Brown University and M.D. and Ph.D. from University of California, San Francisco. He completed his Ph.D. thesis work in the laboratory of John Rubenstein studying the gene regulatory networks involved in early cortical patterning.

Zhuzhu Zhang, Ph.D.
Zhuzhu Zhang is a postdoctoral research fellow at the Salk Institute for Biological Studies working with Joseph Ecker and Edward Callaway. She is broadly interested in understanding the epigenetic and transcriptional regulation in the mammalian brain at single-cell resolution, using both experimental and computational approaches. Specifically, Zhang studies the neuronal cell types and functions in the brain and investigates their molecular signatures in the context of neural pathways and circuits by developing and deploying novel single cell multi-omics approaches. She plans to further investigate cell type- and circuit-specific epigenetic regulations in normal postnatal brain development and in neurodevelopmental disorders and explore epigenetic mechanisms that underlie genotype-environment (GxE) interaction.

2020
Neir Eshel, M.D., Ph.D.
Neir Eshel is an instructor in the Department of Psychiatry and Behavioral Sciences at Stanford University. He received his A.B. from Princeton University, M.S. from University College London, and M.D./Ph.D. from Harvard University.

Ranmal Aloka Samarasinghe, M.D., Ph.D.
Ranmal Aloka Samarasinghe is a clinical instructor at the University of California, Los Angeles (UCLA). He received his M.D. and Ph.D. from the University of Pittsburgh in 2013. He performed his thesis research in the laboratory of Donald DeFranco, where he studied nongenomic actions of glucocorticoid hormones in neural progenitor cells.

Toni-Lee Sterley, Ph.D.
Toni-Lee Sterley is a postdoctoral associate at the University of Calgary. She completed her doctoral training in the laboratory of Vivienne Russell at the University of Cape Town. Her doctoral thesis used rodent models to investigate the influences of early life stress and genetic predispositions in the development of attention-deficit/hyperactivity disorder or depression, specifically looking at roles for glutamatergic and GABAergic transmission in observed behavioral phenotypes.

2019
Nicholas Frost, M.D., Ph.D.
Nicholas Frost is an adjunct clinical instructor at the University of California, San Francisco. He received his M.D. and Ph.D. at the University of Maryland School of Medicine. There, his thesis work in the laboratory of Thomas Blanpied focused on the regulation of actin polymerization within dendritic spines, utilizing super-resolution microscopy to track single molecules of polymerized actin moving within living neurons.

Ethan Greenblatt, Ph.D.
Ethan Greenblatt is an assistant professor at the University of British Columbia. He received his doctoral training in the laboratory of Ron Kopito at Stanford University, where he worked on cellular protein quality control mechanisms, showing a central role for membrane ‘pseudo’-proteases in the proteasomal degradation of misfolded secretory proteins.

Fenna Krienen, Ph.D.
Fenna Krienen is a postdoctoral fellow at Harvard Medical School. She received her B.A. from the University California, Berkeley and completed her doctoral studies at Harvard University with Randy Buckner, where she used noninvasive neuroimaging to infer principles of corticocortical and corticocerebellar network architecture in the human brain.

J. Elliott Robinson, M.D., Ph.D.
J. Elliott Robinson is an assistant professor at Cincinnati Children's Hospital, University of Cincinnati School of Medicine. He completed his M.D. and Ph.D. in the Medical Scientist Training Program at the University of North Carolina (UNC) at Chapel Hill. His doctoral dissertation work, which was co-advised by C.J. Malanga (UNC) and Markus Heilig (National Institute on Alcohol Abuse and Alcoholism), investigated how the A118G mu opioid receptor gene polymorphism moderates dopaminergic and behavioral responses to alcohol and abused opioids.

Hume Stroud, Ph.D.
Hume Stroud is an assistant professor at the University of Texas Southwestern Medical Center. He received his doctoral training in the laboratory of Steve Jacobsen at the University of California, Los Angeles. His work focused on the regulation of DNA replication and transposon silencing in the model plant Arabidopsis thaliana. For his postdoctoral training, Stroud went on to join the laboratory of Michael Greenberg at Harvard Medical School, where he utilized genomic approaches to understand the regulation and function of DNA methylation in neurons in the developing brain.

2018
Reza Kalhor, Ph.D.
Reza Kalhor is an assistant professor at Johns Hopkins University. His lab develops new tools using a variety of strategies, including molecular engineering, CRISPR-based manipulation and computational approaches. These tools are then applied to problems in mammalian development, neurobiology and synthetic biology.

Xin Tang, Ph.D.
Xin Tang is an assistant professor at Harvard Medical School. He studies genetic and environmental factors regulating synaptic signal transmission, with a focus on KCC2 molecular pathways and the role of KCC2 dysregulation in autism spectrum disorder.

Donna Werling, Ph.D.
Donna Werling is an assistant professor at the University of Wisconsin–Madison. Her research is focused on understanding the key neurobiological mechanisms involved in the etiology of ASD and other neurodevelopmental disorders, including genetic and developmental processes, with a focus on the role of sex-differential biology in modulating risk.

Peng Zhang, Ph.D.
Peng Zhang is interested in the role of extracellular matrix glycans in shaping synaptic properties and brain function. During his Ph.D., Zhang studied the role of O-mannosylated glycans on a-dystroglycan in regulating binding to laminin, and the assembly of the extracellular matrix, which is an underlying pathological mechanism in congenital muscular dystrophies. Subsequently, Zhang extended his interests in this area to the field of synaptic development in Ann Marie Craig’s laboratory. He discovered that neurexins (a class of synaptic adhesion molecules) are modified by a rare type of glycan called heparan sulfate, which is a constituent of the extracellular matrix.

2017
Ryan Doan, Ph.D.
Ryan Doan is an Instructor at Boston Children's Hospital. Doan’s research focuses on the important issue of understanding why many individuals with neurodevelopmental disorders lack a genetic diagnosis, both in clinical and research settings. The overall aim of his laboratory is to develop and implement a streamlined approach combining evolutionary and human genetics to discover novel noncoding mutations that can be targeted in a clinical diagnostic setting.

Michael Hart, Ph.D.
Michael Hart is a research associate at the University of Pennsylvania and a member of the Autism Spectrum Program of Excellence (ASPE). Hart’s research utilizes the nematode C. elegans to study and model disease genes and disease variants associated with autism spectrum disorder.

Rebecca Muhle, M.D., Ph.D.
Rebecca Muhle is an assistant professor at Columbia University. Muhle works with individuals with neurodevelopmental conditions such as autism spectrum disorder (ASD) and uses animal and cellular model systems to uncover the biological changes that occur when genes associated with ASD are disrupted.

Gabriela Rosenblau, Ph.D.
Gabriela Rosenblau is an assistant professor of cognitive neuroscience in the psychology department at George Washington University. Her research combines computational models with functional neuroimaging to further our mechanistic understanding of typical and atypical human development and learning.

Stephanie Rudolph, Ph.D.
Stephanie Rudolph is an assistant professor at Albert Einstein College of Medicine. Rudolph uses a combination of genetic, viral, in vitro and in vivo techniques to assess neuromodulatory system interactions with, and effects on, cerebellar non-motor functions in mouse models of autism spectrum disorder.

Seth Shipman, Ph.D.
Seth Shipman is an assistant investigator at the Gladstone Institute and an assistant professor in bioengineering and therapeutic sciences at the University of California, San Francisco (UCSF). His lab engineers new functions into living cells to understand the fundamental biology of developing systems, particularly the brain.

Tingting Wang, Ph.D.
Tingting Wang is an assistant professor in the Department of Pharmacology & Physiology at Georgetown University. Her lab investigates the molecular mechanisms that underlie the homeostatic control of the nervous system and studies how impaired homeostatic plasticity may contribute to brain disorders, including autism.

2016
Sung Eun (Samuel) Kwon, Ph.D.
Sung Eun “Samuel” Kwon is an assistant professor in the Department of Molecular, Cellular and Developmental Biology at the University of Michigan, Ann Arbor. Kwon focuses on cellular, molecular and circuit mechanisms underlying sensory cortical plasticity in both health and conditions of neurocognitive disorders using in vivo imaging, electrophysiology, opto- and pharmaco-genetics, and behavior in the mammalian brain.

Michael Gandal, M.D., Ph.D.
Michael Gandal is an assistant professor at University of California, Los Angeles, and at the Semel Institute for Neuroscience and Human Behavior. His group uses systems-level genetic, genomic and transcriptomic approaches to understand the neurobiological mechanisms underlying autism, schizophrenia and related neurodevelopmental psychiatric disorders.

Yun Li, Ph.D.
Yun Li is an assistant professor at the University of Toronto and a scientist at the Hospital for Sick Children. Li’s laboratory utilizes a combination of pluripotent stem cell technology, genome editing and three-dimensional organoid culture systems to understand how the human brain forms, what makes it unique from that of other species and how disorders like autism impact human brain development and function.

Tomasz Nowakowski, Ph.D.
Tomasz Nowakowski is an assistant professor at the University of California, San Francisco. Nowakowski pioneered the use of single cell RNA sequencing to study the heterogeneity of cellular populations in the developing brain. His research focuses on understanding how the human genome reproducibly generates diverse neuronal populations and how genome abnormalities affecting these developmental processes cause developmental neuropsychiatric disorders like autism.

Rui Peixoto, Ph.D.
Rui Peixoto is an assistant professor at the University of Pittsburgh. His laboratory is focused on investigating the disruption of basal ganglia maturation by cortical hyperactivity in autism spectrum disorder.

Aakanksha Singhvi, Ph.D.
Aakanksha Singhvi is an assistant member at the Fred Hutchinson Cancer Research Center. Singhvi’s laboratory focuses on understanding — at both a molecular and mechanistic level in C. elegans — how glia and neurons communicate with each other to regulate sensory perception, neuronal physiology, neural circuit activity, memory formation and animal behavior in both healthy and neurological disease states.

2015
Renata Batista-Brito, Ph.D.
Renata Batista-Brito is an assistant professor at Albert Einstein College of Medicine. Her lab combines cell-type specific manipulation of neuronal activity, in vivo electrophysiology, in vivo 2-photon imaging and behavioral analysis in order to understand how the postnatal developmental of inhibition shapes sensory representation in the mature brain and how this process is altered in neurodevelopmental disorders.

Graham Diering, Ph.D.
Graham Diering is an assistant professor at University of Carolina, Chapel Hill. He studies the molecular mechanisms of synaptic plasticity, with a particular interest in sleep. Using mouse models of human disease as well as primary cultured neurons, Diering applies his work to understanding and treating neurodevelopmental disorders, including autism and intellectual disability. He broadly studies biochemistry, pharmacology, animal behavior and genetics.

Sung Han, Ph.D.
Sung Han is an assistant professor at the Salk Institute for Biological Studies. His lab is interested in dissecting neural circuits that transmit aversive sensory signals to the brain.

Keren Haroush, Ph.D.
Keren Haroush is an assistant professor at Stanford University. Her laboratory studies the mechanisms by which highly complex behaviors are mediated at the neuronal level, mainly focusing on the example of dynamic social interactions and the neural circuits that drive them.

Holly Stessman, Ph.D.
Holly Stessman is an assistant professor at Creighton University, where she leads a research group identifying and functionally characterizing genetic variation that contributes to ASD disease biology.

Jason Yi, Ph.D.
Jason Yi is an assistant professor in the Department of Neuroscience at Washington University School of Medicine in St. Louis. His laboratory is broadly interested in the molecular pathways that shape nervous system development and function, with the ultimate goal of understanding how dysfunction in these pathways contributes to disease.
