BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//SFARI - ECPv6.6.3//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:SFARI
X-ORIGINAL-URL:https://www.sfari.org
X-WR-CALDESC:Events for SFARI
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:UTC
BEGIN:STANDARD
TZOFFSETFROM:+0000
TZOFFSETTO:+0000
TZNAME:UTC
DTSTART:20150101T000000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=UTC:20191030T170000
DTEND;TZID=UTC:20191030T181500
DTSTAMP:20260403T192017
CREATED:20190924T093053Z
LAST-MODIFIED:20191112T165726Z
UID:18986-1572454800-1572459300@www.sfari.org
SUMMARY:Neuroimmune interactions shaping social behavior in mouse models for neurodevelopmental disorders
DESCRIPTION:
URL:https://www.sfari.org/event/neuroimmune-interactions-shaping-social-behavior-in-mouse-models-for-neurodevelopmental-disorders/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/10/20162135/Portrait_Choi.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20191021T183000
DTEND;TZID=UTC:20191021T203000
DTSTAMP:20260403T192017
CREATED:20190927T180631Z
LAST-MODIFIED:20191001T191624Z
UID:18954-1571682600-1571689800@www.sfari.org
SUMMARY:SFARI Society for Neuroscience 2019 Social
DESCRIPTION:
URL:https://www.sfari.org/event/sfari-society-for-neuroscience-2019-social/
LOCATION:Marriott Marquis Chicago\, 2121 S Prairie Ave\, Chicago\, 60616\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2019/09/25180919/IMG_3744.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190614T120000
DTEND;TZID=UTC:20190614T130000
DTSTAMP:20260403T192017
CREATED:20190624T210253Z
LAST-MODIFIED:20210525T203530Z
UID:18062-1560513600-1560517200@www.sfari.org
SUMMARY:SFARI Viewer - an online platform to visualize and analyze SFARI genomic data
DESCRIPTION:
URL:https://www.sfari.org/event/sfari-viewer-an-online-platform-to-visualize-and-analyze-sfari-genomic-data/
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190424T170000
DTEND;TZID=UTC:20190424T181500
DTSTAMP:20260403T192017
CREATED:20190424T220330Z
LAST-MODIFIED:20190718T201402Z
UID:16785-1556125200-1556129700@www.sfari.org
SUMMARY:Altered somatosensory processing in autism spectrum disorders: Mechanisms and emerging therapeutic opportunities
DESCRIPTION:
URL:https://www.sfari.org/event/altered-somatosensory-processing-in-autism-spectrum-disorders-mechanisms-and-emerging-therapeutic-opportunities/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/png:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/08204842/Screen-Shot-2019-03-08-at-3.42.39-PM.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190403T170000
DTEND;TZID=UTC:20190403T181500
DTSTAMP:20260403T192017
CREATED:20190403T154301Z
LAST-MODIFIED:20190617T161632Z
UID:18024-1554310800-1554315300@www.sfari.org
SUMMARY:Mapping human cerebral cortex: Structure\, function\, connectivity\, development and evolution
DESCRIPTION:
URL:https://www.sfari.org/event/mapping-human-cerebral-cortex-structure-function-connectivity-development-and-evolution/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/png:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2019/06/17154100/VanEssen_500_crop.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20190130T170000
DTEND;TZID=UTC:20190130T181500
DTSTAMP:20260403T192017
CREATED:20190113T202252Z
LAST-MODIFIED:20190702T152504Z
UID:12065-1548867600-1548872100@www.sfari.org
SUMMARY:The genetic influences on autism spectrum disorder risk
DESCRIPTION:
URL:https://www.sfari.org/event/the-genetic-influences-on-autism-spectrum-disorder-risk/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2018/02/13182029/Elise-Robinson-e1518548967942.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20181212T170000
DTEND;TZID=UTC:20181212T181500
DTSTAMP:20260403T192017
CREATED:20181127T160037Z
LAST-MODIFIED:20190624T210729Z
UID:15358-1544634000-1544638500@www.sfari.org
SUMMARY:The predictive impairment hypothesis in autism: An empirical assessment
DESCRIPTION:
URL:https://www.sfari.org/event/the-predictive-impairment-hypothesis-in-autism-an-empirical-assessment/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20181128T170000
DTEND;TZID=UTC:20181128T181500
DTSTAMP:20260403T192017
CREATED:20181106T154521Z
LAST-MODIFIED:20181217T223518Z
UID:15057-1543424400-1543428900@www.sfari.org
SUMMARY:Rethinking autism and animal models: A systems perspective
DESCRIPTION:
URL:https://www.sfari.org/event/rethinking-autism-and-animal-models-a-systems-perspective/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2018/11/06153257/Fenton-2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20181105T183000
DTEND;TZID=UTC:20181105T203000
DTSTAMP:20260403T192017
CREATED:20181024T200857Z
LAST-MODIFIED:20191001T191023Z
UID:14672-1541442600-1541449800@www.sfari.org
SUMMARY:SFARI Society for Neuroscience 2018 Social
DESCRIPTION:
URL:https://www.sfari.org/event/sfari-society-for-neuroscience-2018-social/
LOCATION:Hilton San Diego Bayfront Indigo 204\, One Park Blvd\, San Diego\, CA\, 92101\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2018/10/19140853/171113_Simons_Reception_054.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20180926T170000
DTEND;TZID=UTC:20180926T181500
DTSTAMP:20260403T192017
CREATED:20180828T162423Z
LAST-MODIFIED:20181130T155452Z
UID:14198-1537981200-1537985700@www.sfari.org
SUMMARY:Thinking differently about neurodevelopmental disorders and autism: Lumping vs. splitting
DESCRIPTION:
URL:https://www.sfari.org/event/thinking-differently-about-neurodevelopmental-disorders-and-autism-lumping-vs-splitting/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2018/08/28160311/Evdokia_headshot.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20180410T083500
DTEND;TZID=UTC:20180410T085000
DTSTAMP:20260403T192017
CREATED:20180709T160155Z
LAST-MODIFIED:20180711T203358Z
UID:13538-1523349300-1523350200@www.sfari.org
SUMMARY:Autism genetics: Where have we been and where are we going?
DESCRIPTION:
URL:https://www.sfari.org/event/autism-genetics-where-have-we-been-and-where-are-we-going/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/png:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2018/07/11203254/Screen-Shot-2018-07-11-at-4.31.54-PM-e1531341229842.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20180207T170000
DTEND;TZID=UTC:20180207T181500
DTSTAMP:20260403T192017
CREATED:20180104T162448Z
LAST-MODIFIED:20180828T145113Z
UID:11600-1518022800-1518027300@www.sfari.org
SUMMARY:On the road to precision health: Brain-based biomarkers in autism spectrum disorder
DESCRIPTION:
URL:https://www.sfari.org/event/on-the-road-to-precision-health-brain-based-biomarkers-in-autism-spectrum-disorder/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2018/01/04153249/Shafali_Jeste_Portraits-2h.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20180124T170000
DTEND;TZID=UTC:20180124T181500
DTSTAMP:20260403T192017
CREATED:20180103T191913Z
LAST-MODIFIED:20180213T152024Z
UID:11570-1516813200-1516817700@www.sfari.org
SUMMARY:Arousal\, emotion regulation and challenging behaviors: Insights from the Autism Inpatient Collection
DESCRIPTION:
URL:https://www.sfari.org/event/arousal-emotion-regulation-and-challenging-behaviors-insights-from-the-autism-inpatient-collection/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/png:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2018/01/03145156/matthewsiegel.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20171128T170000
DTEND;TZID=UTC:20171128T180000
DTSTAMP:20260403T192017
CREATED:20171027T205726Z
LAST-MODIFIED:20180216T145936Z
UID:10599-1511888400-1511892000@www.sfari.org
SUMMARY:Autism genetics: Searching for coherence
DESCRIPTION:
URL:https://www.sfari.org/event/autism-genetics-searching-for-coherence/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/21183802/dgeschwind.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20171113T183000
DTEND;TZID=UTC:20171113T203000
DTSTAMP:20260403T192017
CREATED:20171024T143634Z
LAST-MODIFIED:20181018T142326Z
UID:10429-1510597800-1510605000@www.sfari.org
SUMMARY:SFARI Society for Neuroscience 2017 Social
DESCRIPTION:  \n\nAll Society for Neuroscience (SfN) attendees are welcome to join SFARI Investigators and scientific staff for an evening of socializing and networking\, including a brief information session on SFARI funding opportunities and scientific resources for the autism research community. \nWe welcome newcomers to autism research as well as those already working to uncover the science of autism spectrum disorders. \nSimons Foundation staff will be available to answer questions about the work SFARI currently funds\, future opportunities for funding and SFARI resources. \n\n\n\n \nA number of SFARI Investigators will be presenting their research at Neuroscience 2016.To find out more\, click here.\n\n\n\nSFARI + SfN Social\nDate: Monday\, 13 November 2017\nTime: 6:30 p.m. – 8:30 p.m.\nMarriott Marquis Washington\, D.C.\nLiberty Salons I\, J\, K \nQuestions? Contact communications@simonsfoundation.org. \nWe look forward to seeing you there. \n\n\n 
URL:https://www.sfari.org/event/sfari-society-for-neuroscience-2017-social/
LOCATION:Marriott Marquis Washington\, D.C. Liberty Salons I\, J\, K\, 901 Massachusetts Ave NW\, Washington\, D.C.\, 20001\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/10/08200947/sfn2017social-1100.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20171101T170000
DTEND;TZID=UTC:20171101T181500
DTSTAMP:20260403T192017
CREATED:20171013T145814Z
LAST-MODIFIED:20171129T145650Z
UID:10044-1509555600-1509560100@www.sfari.org
SUMMARY:Understanding autism and other neurodevelopmental disorders: From the embryo to brain organoids
DESCRIPTION:
URL:https://www.sfari.org/event/understanding-autism-and-other-neurodevelopmental-disorders-from-the-embryo-to-brain-organoids/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/21184833/paolaarlotta.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20171011T170000
DTEND;TZID=UTC:20171011T181500
DTSTAMP:20260403T192017
CREATED:20170906T132823Z
LAST-MODIFIED:20180706T160059Z
UID:8943-1507741200-1507745700@www.sfari.org
SUMMARY:Leveraging long-term health data and exome sequencing for autism-related gene discovery
DESCRIPTION:
URL:https://www.sfari.org/event/leveraging-long-term-health-data-and-exome-sequencing-for-autism-related-gene-discovery/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/18162559/DavidLedbetter250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20170322T170000
DTEND;TZID=UTC:20170322T181500
DTSTAMP:20260403T192017
CREATED:20170322T040000Z
LAST-MODIFIED:20180216T145520Z
UID:2008-1490202000-1490206500@www.sfari.org
SUMMARY:What can genetics tell us about autism spectrum disorder?
DESCRIPTION:  \n\nOn 22 March 2017\, Stephan Sanders presented an update on the current state of genetics research in autism\, highlighting some of the key findings that remain to be discovered\, and discussing how these findings could ultimately benefit individuals with autism and their families. \nHis talk was part of the Simons Foundation Autism Research lecture series. \nAbout the Lecture\nIt has been known that autism spectrum disorder is primarily caused by genetic factors for several decades. The past 10 years have seen great progress in finding some of the genes responsible and in building a map of what other types of genetic variants may contribute. These findings have been used both to provide insight into the biology of autism and\, in the clinic\, to identify individuals with specific genetic variants. \nIn this lecture\, Stephan Sanders presented an update on the current state of genetics research in autism\, highlight some of the key findings that remain to be discovered\, and discussing how these findings could ultimately benefit individuals with autism and their families. \nAbout the speaker:\nStephan Sanders trained as a pediatric physician in the United Kingdom before pursuing a research career in genomics and bioinformatics. His work has helped characterize the role of de novo mutations in the etiology of autism and identified multiple autism risk loci\, including duplications of the 7q11.23 Williams syndrome region (Sanders et al.\, Neuron\, 2011) and mutations in the sodium channel gene SCN2A (Sanders et al.\, Nature\, 2012). His work on the integration of copy number variation and exome data across multiple autism cohorts recently identified 71 autism risk loci (Sanders et al.\, Neuron\, 2015). In addition\, he worked as part of a group that integrated spatiotemporal gene expression data from the human brain with these autism-associated genes (Willsey et al.\, Cell\, 2013). This approach has implicated deep-layer glutamatergic neurons in the frontal cortex during mid-fetal development in the causation of autism. \nHis lab has three main research aims: 1) Understanding the genetic basis of childhood neurodevelopmental conditions\, in particular autism; 2) Understanding how these genetic factors lead to the conditions; and 3) Understanding the mechanism that leads to the male bias in autism diagnosis\, in particular through identifying the biological basis of the female protective effect. \n 
URL:https://www.sfari.org/event/what-can-genetics-tell-us-about-autism-spectrum-disorder/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/27205941/stephansanders.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20170222T170000
DTEND;TZID=UTC:20170222T181500
DTSTAMP:20260403T192017
CREATED:20170222T050000Z
LAST-MODIFIED:20180216T151522Z
UID:1993-1487782800-1487787300@www.sfari.org
SUMMARY:Exploiting genetics to identify environmental risks for autism
DESCRIPTION:  \n\nOn 22 February 2017\, Mark Zylka described how candidate environmental risk factors for autism can be identified rationally\, by pinpointing chemicals that interfere with the same molecular pathways that are affected in individuals with autism. \nHis talk was part of the Simons Foundation Autism Research lecture series. \nAbout the Lecture\nOur inability to identify environmental threats to the brain early — before they cause disease — represents one of the major challenges of our time. This challenge is particularly relevant to autism\, which affects 1 in 68 individuals. Heritability studies indicate that environmental factors contribute to autism risk. \nIn this lecture\, Mark Zylka described how candidate environmental risk factors for autism can be identified rationally\, by pinpointing chemicals that interfere with the same molecular pathways that are affected in individuals with autism. His research focuses on identifying environmental-use chemicals that target autism-linked molecular pathways\, using environmental sampling data to assess the exposure threat to people\, and validating risk potential in animal models. \nAbout the speaker:\nMark Zylka is Director of the Neuroscience Center at the University of North Carolina at Chapel Hill. He received his B.S. in biochemistry from Virginia Polytechnic Institute and State University\, and his Ph.D. in neurobiology from Harvard University. While at Harvard\, he identified several of the core circadian-clock genes and determined how these genes contribute to circadian rhythms in mammals. As a postdoctoral fellow at the California Institute of Technology\, he identified a large family of receptors that regulate pain and itch. Zylka’s lab focuses on pain research and studying genetic and environmental risks for autism. \n  \n 
URL:https://www.sfari.org/event/exploiting-genetics-to-identify-environmental-risks-for-autism/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/04163647/MarkZylka250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20170201T170000
DTEND;TZID=UTC:20170201T180000
DTSTAMP:20260403T192017
CREATED:20170828T200109Z
LAST-MODIFIED:20190617T154916Z
UID:8290-1485968400-1485972000@www.sfari.org
SUMMARY:Genomic insights into human cortical development and neurodevelopmental disease
DESCRIPTION:
URL:https://www.sfari.org/event/genomic-insights-into-human-cortical-development-and-neurodevelopmental-disease/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/28213716/ArnoldKriegstein250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20170125T170000
DTEND;TZID=UTC:20170125T181500
DTSTAMP:20260403T192017
CREATED:20170125T050000Z
LAST-MODIFIED:20180216T151620Z
UID:1994-1485363600-1485368100@www.sfari.org
SUMMARY:Potholes and progress on the road to translational treatments in autism spectrum disorder
DESCRIPTION:  \n\nOn 25 January 2017\, Jeremy Veenstra-VanderWeele outlined critical challenges to translating genomic\, cellular\, and animal model research into new treatments for autism spectrum disorder. \nHis talk was part of the Simons Foundation Autism Research lecture series. \nAbout the Lecture\nEmerging genomic and neuroscience findings have delivered hypotheses that are now being tested in autism spectrum disorder (ASD) and related genetic syndromes. Unfortunately\, these clinical trials have not yet yielded positive results\, suggesting a need to step back and evaluate the science of testing new treatments for neurodevelopmental disorders. \nIn this lecture\, Jeremy Veenstra-VanderWeele outlined critical challenges\, both conceptual and practical\, to translating genomic\, cellular\, and animal model research into new treatments for ASD. He discussed the limitations to conclusions drawn from work in the laboratory as they are extrapolated to the clinic. He also described common pitfalls in clinical trials\, including mismatches between hypotheses and study populations\, substantial “placebo” effects\, and subjective outcome measures. Framing these challenges in the context of past successes in ASD treatment research\, he suggested guideposts as we work toward neurobiologically based treatments for ASD. \nAbout the speaker:\nJeremy Veenstra-VanderWeele is the Mortimer D. Sackler\, M.D.\, Associate Professor in Psychiatry at Columbia University Medical Center and the New York State Psychiatric Institute. He completed his M.D. and residency training at the University of Chicago\, postdoctoral training in neuroscience at Vanderbilt University\, and moved to Columbia in 2014. As a child psychiatrist and developmental neuroscientist\, his primary motivation is to deliver new treatments to children with autism spectrum disorder and related neurodevelopmental disorders. \n 
URL:https://www.sfari.org/event/potholes-and-progress-on-the-road-to-translational-treatments-in-autism-spectrum-disorder/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/04165902/JeremyVeenstra250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20161114T183000
DTEND;TZID=UTC:20161114T203000
DTSTAMP:20260403T192017
CREATED:20170723T195712Z
LAST-MODIFIED:20181019T182223Z
UID:2013-1479148200-1479155400@www.sfari.org
SUMMARY:SFARI Society for Neuroscience 2016 Social
DESCRIPTION:  \n\nAll Society for Neuroscience (SfN) attendees are welcome to join SFARI Investigators and scientific staff for an evening of socializing and networking\, including a brief information session on SFARI funding opportunities and scientific resources for the autism research community. \nWe welcome newcomers to autism research as well as those already working to uncover the science of autism spectrum disorders. \nSimons Foundation staff will be available to answer questions about the work SFARI currently funds\, future opportunities for funding and SFARI resources. \n\n\n\n \nA number of SFARI Investigators will be presenting their research at Neuroscience 2016. \nTo find out more\, click here.\n\n\n\nSFARI + SfN Social\nDate: Monday\, 14 November 2016\nTime: 6:30 p.m. – 8:30 p.m.\nHilton San Diego Bayfront\nIndigo 204 \nQuestions? Contact communications@simonsfoundation.org. \nWe look forward to seeing you there. \n\n\n 
URL:https://www.sfari.org/event/sfari-society-for-neuroscience-2016-social/
LOCATION:Hilton San Diego Bayfront Indigo 204\, One Park Blvd\, San Diego\, CA\, 92101\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/04182158/SfN2016-250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20161102T170000
DTEND;TZID=UTC:20161102T181500
DTSTAMP:20260403T192017
CREATED:20161102T040000Z
LAST-MODIFIED:20180216T151644Z
UID:2010-1478106000-1478110500@www.sfari.org
SUMMARY:How immune cells help wire the brain: Implications for autism and psychiatric illness
DESCRIPTION:  \nOn 2 November 2016\, Beth Stevens discussed recent work that implicates brain immune cells\, called microglia\, in sculpting of synaptic connections during development and their relevance to autism\, schizophrenia and other brain disorders. \nHer talk was part of the Simons Foundation Autism Research lecture series. \nAbout the Lecture\nRecent research has revealed a key role for microglia and a group of immune-related molecules\, called complement\, in normal developmental synaptic pruning\, a process required to establish precise brain wiring. Emerging evidence from Beth Stevens’ lab and others suggest aberrant regulation of this pruning pathway may contribute to synaptic and cognitive dysfunction in a host of brain disorders\, including schizophrenia. Studies also suggest that a person’s risk of schizophrenia is increased if he or she inherits specific variants in complement C4\, which plays a well-known role in the immune system but also helps sculpt developing synapses in the mouse visual system. \nTogether these findings may help explain known features of schizophrenia\, including reduced numbers of synapses in key cortical regions and an adolescent age of onset that corresponds with developmentally timed waves of synaptic pruning in these regions. Stevens discussed this and ongoing work to understand the mechanisms by which complement and microglia prune specific synapses in the brain. A deeper understanding of how these immune mechanisms mediate synaptic pruning may provide novel insight into how to protect synapses in autism and other brain disorders. \nAbout the speaker\nBeth Stevens is an assistant professor of neurology at Harvard Medical School and the F.M. Kirby Neurobiology Center at Boston Children’s Hospital and a member of the Broad Institute. Her laboratory seeks to understand how neuron-glia communication facilitates the formation\, elimination and plasticity of synapses during both healthy development and disease states. Stevens is a recipient of several young investigator awards\, including the Ellison Medical Foundation New Scholar in Aging; John Merck Scholar Program; Presidential Early Career Award for Scientists and Engineers; and a MacArthur Fellowship. \n  \n 
URL:https://www.sfari.org/event/how-immune-cells-help-wire-the-brain-implications-for-autism-and-psychiatric-illness/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/04170132/BethStevens250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20161005T170000
DTEND;TZID=UTC:20161005T181500
DTSTAMP:20260403T192017
CREATED:20161005T040000Z
LAST-MODIFIED:20180216T151810Z
UID:1998-1475686800-1475691300@www.sfari.org
SUMMARY:Tuberous Sclerosis: Shedding light on the neural circuitry of autism
DESCRIPTION:  \nOn 5 October 2016\, Mustafa Sahin presented an update on translational research in Tuberous Sclerosis Complex. His talk was part of the Simons Foundation Autism Research lecture series. \nAbout the Lecture\nIn this lecture\, Mustafa Sahin presented the rationale for investigating Tuberous Sclerosis Complex (TSC) as a way to understand the cellular and circuitry alterations underlying autism spectrum disorder. Using a combination of cell culture\, mouse behavior and human electroencephalography (EEG) and magnetic resonance imaging (MRI) experiments\, Sahin and colleagues have demonstrated abnormalities in neuronal connectivity and neuron-glia interactions in TSC. Inhibitors of mammalian target of rapamycin (mTOR) proteins are effective in mouse models of TSC and are being tested in clinical trials now. A better understanding of TSC can also provide insights for related neurodevelopmental disorders in which similar cellular and circuit abnormalities can be detected. \nAbout the Speaker\nMustafa Sahin is a developmental neurobiologist and a pediatric neurologist. He received his B.S. degree from Brown University\, his M.D. and Ph.D. from Yale School of Medicine. He completed a pediatrics residency at Children’s Hospital of Philadelphia and a child neurology residency at Boston Children’s Hospital. He is currently the director of the Translational Neuroscience Center at Boston Children’s Hospital and a professor of neurology at Harvard Medical School. He directs two national consortia to study biomarkers and comparative pathobiology of TSC and related neurodevelopmental disorders. \n  \n  \n  \n 
URL:https://www.sfari.org/event/tuberous-sclerosis-shedding-light-on-the-neural-circuitry-of-autism/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/04170403/MustafaSahin250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160907T170000
DTEND;TZID=UTC:20160907T181500
DTSTAMP:20260403T192017
CREATED:20160907T040000Z
LAST-MODIFIED:20180216T151922Z
UID:2002-1473267600-1473272100@www.sfari.org
SUMMARY:Sleep in autism spectrum disorders: A window to etiology\, diagnosis and treatment
DESCRIPTION:  \nOn 7 September 2016\, Ruth O’Hara discussed the field’s current understanding of sleep in autism spectrum disorder. \nHer talk was part of the Simons Foundation Autism: Emerging Concepts lecture series. \nAbout the Lecture\nUnderstanding sleep physiology in autism spectrum disorder (ASD) not only provides a window to the underlying etiology\, it can also help characterize sub-phenotypes and offer a potent treatment approach for improving neuropsychiatric and neurocognitive function in ASD through improved sleep. \nRuth O’Hara discussed the field’s current understanding of sleep in ASD\, including: a) describing how sleep physiology in ASD differs from sleep physiology in typically developing children; b) discussing the different potential ASD phenotypes suggested by her work; and c) describing the different sleep architecture\, sleep disturbances\, and sleep disorders that are more prevalent in ASD than in typically developing children and which can serve as treatment targets that may in turn improve the core symptoms of ASD. \nAbout the speaker:\nRuth O’Hara is associate professor and associate chair of the Department of Psychiatry at Stanford University. Her research integrates measures of sleep physiology\, the brain and behavior across the lifespan. Over the years she has obtained substantial National Institutes of Health (NIH) funding to support her work. O’Hara received a SFARI grant to examine sleep physiology and neurodevelopmental processes in autism spectrum disorder. She was a member of the most recent Diagnostic and Statistical Manual of Mental Disorders (DSM) sleep-wake disorders work group. \n  \n  \n 
URL:https://www.sfari.org/event/sleep-in-autism-spectrum-disorders-a-window-to-etiology-diagnosis-and-treatment/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/04170635/RuthOHara250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160427T170000
DTEND;TZID=UTC:20160427T181500
DTSTAMP:20260403T192017
CREATED:20160427T040000Z
LAST-MODIFIED:20180216T145622Z
UID:1996-1461776400-1461780900@www.sfari.org
SUMMARY:One brain\, many genomes: Somatic mutation and genomic variability in human cerebral cortex
DESCRIPTION:  \nOn 27 April 2016\, Christopher Walsh reviewed recent work on ‘somatic mutations’ — de novo mutations that are present in some brain cells but not in all cells of the body — in several neurological conditions associated with intellectual disability and seizures. \nHis talk was part of the Simons Foundation Autism Research lecture series. \nAbout the Lecture\nChristopher Walsh and his team are interested in genetic mechanisms of cerebral cortical development and abnormalities of cortical development resulting in intellectual disability\, autism and epilepsy. The lab pioneered the analysis of recessive causes of autism by studying children with autism whose parents share ancestry. \nIn this lecture\, Walsh reviewed recent work on ‘somatic mutations’ — de novo mutations that are present in some brain cells but not in all cells of the body — in several neurological conditions associated with intellectual disability and seizures. His talk also covered the extent to which somatic mutations are an inevitable part of normal brain development\, such that the neurons in the human brain are a tapestry of cells with distinct genomes. The relevance of somatic mutations to autism was also discussed. \nAbout the Speaker\nChristopher A. Walsh is Chief of the Division of Genetics and Genomics at Boston Children’s Hospital\, Bullard Professor of Pediatrics and Neurology at Harvard Medical School\, and an investigator of the Howard Hughes Medical Institute. He completed the M.D. and Ph.D. degrees at the University of Chicago\, trained in neurology at Massachusetts General Hospital\, and has been at Children’s Hospital since 2006. \n  \n  \n  \n 
URL:https://www.sfari.org/event/one-brain-many-genomes-somatic-mutation-and-genomic-variability-in-human-cerebral-cortex/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/04171435/ChristopherWalsh250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160330T170000
DTEND;TZID=UTC:20160330T181500
DTSTAMP:20260403T192017
CREATED:20160330T040000Z
LAST-MODIFIED:20180216T151954Z
UID:1997-1459357200-1459361700@www.sfari.org
SUMMARY:Development begins before birth: Prenatal research relevant to autism
DESCRIPTION:  \nOn 30 March 2016\, Catherine Monk described her lab’s fetal origins of adult disease (FOAD) studies that focus on women in the perinatal period and fetal and infant neurobehavioral development\, including direct studies of the fetus\, newborn brain imaging and placental methylation. Her talk was part of the Simons Foundation Autism Research lecture series. \nAbout the Lecture\nThe burgeoning research field known as the fetal origins of adult disease (FOAD) or the developmental origins of health and disease (DOHAD) demonstrates that maternal distress during pregnancy affects fetal and infant brain–behavior development. This is a ‘third pathway’ for the familial inheritance of psychiatric illness beyond shared genes and the quality of parental care\, and one that\, if fully understood\, could lead to early prevention of developmental risk. \nIn this lecture\, Catherine Monk described her lab’s FOAD studies that focus on women in the perinatal period and fetal and infant neurobehavioral development\, including direct studies of the fetus\, newborn brain imaging and placental methylation. \nApplying the FOAD model to autism research introduces the possibility of identifying perinatal markers for the disorder and may help advance the animal and epidemiological findings showing that prenatal maternal immune activation — often a correlate of distress — is associated with risk for the illness. \nAbout the Speaker\nCatherine Monk\, Ph.D.\, holds a joint appointment as an associate professor in the Departments of Psychiatry\, and Obstetrics & Gynecology at Columbia University Medical Center. Reflecting the interdisciplinary nature of her research\, she is affiliated with two divisions in psychiatry: behavioral medicine and developmental neuroscience. She is director for research at the Women’s Program\, as well as co–director of the Sackler Parent–Infant Project and of the Domestic Violence Initiative. After completing her National Institutes of Health postdoctoral fellowship in the psychobiological sciences at Columbia in 2000\, Dr. Monk joined the faculty and established the Perinatal Pathways Laboratory. \n  \n  \n  \n 
URL:https://www.sfari.org/event/development-begins-before-birth-prenatal-research-relevant-to-autism/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/08/04212510/CatherineMonk250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160127T170000
DTEND;TZID=UTC:20160127T181500
DTSTAMP:20260403T192017
CREATED:20160127T050000Z
LAST-MODIFIED:20190617T151309Z
UID:2005-1453914000-1453918500@www.sfari.org
SUMMARY:Making up your mind: Interneurons in development and disease
DESCRIPTION:  \nOn 27 January 2016\, Gordon Fishell described his investigations of the developmental and genetic origins of interneuron development. His talk was part of the Simons Foundation Autism Research lecture series. \nAbout the Lecture\nInterneurons within the brain\, in the cortex and hippocampus in particular\, are central for normal brain function\, and conversely\, dysfunction of these cell types is thought to result in developmental neurological disorders. The Fishell laboratory combines genetic and physiological approaches to examine the origins of these populations and their integration into brain circuitry. \nIn this lecture\, Gordon Fishell described his investigations of the developmental and genetic origins of interneuron development. This process begins with their specification\, during which genetic programs initiated within progenitors relegate interneurons into specific cardinal classes. Subsequent to this\, neuronal activity is fundamental for both the laminar positioning as well as the dendritic and axonal arborization in at least some interneuron subtypes. Fishell’s findings suggest that sensory information complements earlier established genetic programs to shape the way interneuronal subtypes integrate into nascent cortical circuits. Importantly\, many of the genes involved in the maturation of interneurons appear to also be implicated in neuropsychiatric diseases\, including autism and schizophrenia. \nAbout the Speaker\nGordon J. Fishell\, Ph.D.\, is associate director of the NYU Neuroscience Institute\, Julius Raines Professor of Neuroscience and Physiology\, and director of the Graduate Program in Neuroscience and Physiology at New York University (NYU) School of Medicine. Fishell is a long-standing member of the NYU School of Medicine community\, having joined the developmental genetics program in the Skirball Institute of Biomolecular Medicine in 1994. In 2006\, he launched the Smilow Neuroscience Program\, and in 2011 he became associate director of the then-newly-formed NYU Neuroscience Institute. \n  \n  \n 
URL:https://www.sfari.org/event/making-up-your-mind-interneurons-in-development-and-disease/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/04171933/GordanFishell250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20151111T170000
DTEND;TZID=UTC:20151111T181500
DTSTAMP:20260403T192017
CREATED:20151111T050000Z
LAST-MODIFIED:20180216T152100Z
UID:2003-1447261200-1447265700@www.sfari.org
SUMMARY:Storming the ivory tower: How to make autism interventions work in schools
DESCRIPTION:  \nOn 11 November 2015\, David S. Mandell talked about why autism interventions rarely are implemented in community practice and why they fail to achieve the same outcomes as those observed in clinical trials.  \nHis talk was part of the Simons Foundation Autism Research lecture series. \nAbout the Lecture\nA growing body of research shows the efficacy of interventions for children with autism. These interventions rarely make their way into community practice\, however. When they do\, they usually do not produce the same results as those observed in clinical trials. \nIn this lecture\, David S. Mandell will talk about why autism interventions rarely are implemented in community practice and why they fail to achieve the same outcomes as those observed in clinical trials. He will review the policy environment for improving quality of care and evidence suggesting that recently enacted policies may be necessary but are not sufficient to improve practice. He also will present research that more directly attempts to improve quality of care and associated outcomes for children with autism. \nAbout the Speaker\nDavid S. Mandell\, Sc.D.\, is associate professor of psychiatry and pediatrics at the University of Pennsylvania’s Perelman School of Medicine. The goal of his research is to improve the quality of care that individuals with autism receive in their communities. He examines the effects that different state and federal strategies to organize\, finance and deliver services have on service use patterns and outcomes. He also conducts experimental studies to determine the best ways to successfully implement proven-efficacious practices in community settings. \n  \n  \n  \n 
URL:https://www.sfari.org/event/storming-the-ivory-tower-how-to-make-autism-interventions-work-in-schools/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/08/04211710/DavidMandell250.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20151028T170000
DTEND;TZID=UTC:20151028T181500
DTSTAMP:20260403T192017
CREATED:20151028T040000Z
LAST-MODIFIED:20180216T152152Z
UID:2004-1446051600-1446056100@www.sfari.org
SUMMARY:Molecular and neural architecture of circuits underlying social behavior in the mouse
DESCRIPTION:  \nOn 28 October 2015\, Catherine Dulac discussed the cellular and molecular architecture of neural circuits underlying instinctive social behaviors in mice. Her talk was part of the Simons Foundation Autism Research lecture series. \nAbout the Lecture\nSevere mental disorders such autism spectrum disorders\, schizophrenia and major depressive disorder are characterized by profound social impairments. There is little understanding of the neural mechanisms underlying these social deficits\, and efficient diagnosis and therapeutic options are lacking. Advanced molecular and genetic techniques have made the discovery of specific behavior circuits possible.\nIn this lecture\, Catherine Dulac will discuss the cellular and molecular architecture of neural circuits underlying instinctive social behaviors of mice. She will describe her group’s recent advances in uncovering the identity of sensory neurons that detect social cues and the identity of command circuits associated with specific social responses in male and female mice. \nAbout the Speaker\nCatherine Dulac received her B.Sc. from the Ecole Normale Superieure in Paris\, France\, her Ph.D. from the University of Paris and was a postdoctoral fellow at Columbia University. She has been a Howard Hughes Medical Institute Investigator since 1997 and a Harvard faculty in the Department of Molecular and Cellular Biology since 1996 (Chair 2007-2013). She is a recipient of the Lounsbery\, Perl-UNC Neuroscience\, and Pradel Research Awards. Memberships include the National Academy of Sciences and the French Academy of Sciences\, and she is a Chevalier de la Legion d’Honneur. \n  \n  \n 
URL:https://www.sfari.org/event/molecular-and-neural-architecture-of-circuits-underlying-social-behavior-in-the-mouse/
LOCATION:Gerald D. Fischbach Auditorium\, 160 5th Avenue\, New York\, NY\, 10010\, United States
ATTACH;FMTTYPE=image/jpeg:https://sf-web-assets-prod.s3.amazonaws.com/wp-content/uploads/sites/2/2017/07/21183821/catherinedulac.jpg
END:VEVENT
END:VCALENDAR